Metastasis occurs when cancer spreads to other parts of the body. Some patients have asked whether scalp cooling increases the chance of metastases in the scalp. 

A study published in 2017 reviewed patients with breast cancer receiving chemotherapy while using scalp cooling for hair preservation and found there was no statistical difference in the incidence of scalp metastasis between patients using scalp cooling vs. no scalp cooling. The study concluded that “based on this extensive review and meta-analysis, scalp cooling is highly unlikely to increase the incidence of scalp metastases in patients with early-stage breast cancer receiving adjuvant chemotherapy.”


The incidence of scalp metastases was low regardless of scalp cooling. This analysis suggests that scalp cooling does not increase the incidence of scalp metastases.

As Published
Scalp cooling with adjuvant/neoadjuvant chemotherapy for breast cancer and the risk of scalp metastases: systematic review and meta-analysis.
Breast Cancer Research and Treatment, 2017: 163:199–205
Rugo, H, et al.

Multiple articles have also appeared in industry publications including; New England Journal of Medicine, Med Tech Intelligence, medGadget, Medical Plastic, and Oncology Nurse Advisor.

Please note that the content of this website is not intended as professional medical or healthcare advice and should not be construed as a substitute for professional healthcare advice, or services from a qualified professional healthcare provider familiar with your unique situation. This content is intended solely as a general product and corporate information.

10925 Estate Lane, Suite 185
Dallas, TX 75238
+1 877-350-2150

Dignitana AB
Traktorgränden 3
226 60 Lund, Sweden
+46 46 16 30 90

Aurora BioScience
PO Box 946
Baulkham Hills NSW 2153
+61 1300 309 994
+64 0800 533 272